Title : Ribofuranosyl-benzimidazole derivatives as inhibitors of casein kinase-2 and casein kinase-1.

Pub. Date : 1990 Jan 12

PMID : 2105215






1 Functional Relationships(s)
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1 Although the inhibitory spectrum of CK-1 by the various analogues is reminiscent of that observed with CK-2, a remarkable difference is revealed by 5"-phosphorylation of ribose which increases the Ki with CK-2 while decreasing that with CK-1. Ribose Calcium-dependent protein kinase 6 Zea mays