Pub. Date : 2010 Nov 5
PMID : 21051640
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | To understand how the ribosome triggers GTP hydrolysis in translational GTPases, we have determined the crystal structure of EF-Tu and aminoacyl-tRNA bound to the ribosome with a GTP analog, to 3.2 angstrom resolution. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 2 | To understand how the ribosome triggers GTP hydrolysis in translational GTPases, we have determined the crystal structure of EF-Tu and aminoacyl-tRNA bound to the ribosome with a GTP analog, to 3.2 angstrom resolution. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 3 | EF-Tu is in its active conformation, the switch I loop is ordered, and the catalytic histidine is coordinating the nucleophilic water in position for inline attack on the gamma-phosphate of GTP. | Guanosine Triphosphate | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |