Title : Quiescent fibroblasts exhibit high metabolic activity.

Pub. Date : 2010 Oct 19

PMID : 21049082






1 Functional Relationships(s)
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1 By feeding the cells labeled glutamine, we also detected a "backwards" flux in the tricarboxylic acid cycle from alpha-ketoglutarate to citrate that was enhanced in contact-inhibited fibroblasts; this flux likely contributes to shuttling of NADPH from the mitochondrion to cytosol for redox defense or fatty acid synthesis. Ketoglutaric Acids 2,4-dienoyl-CoA reductase 1 Homo sapiens