Title : ARHGEF7 (Beta-PIX) acts as guanine nucleotide exchange factor for leucine-rich repeat kinase 2.

Pub. Date : 2010 Oct 29

PMID : 21048939






1 Functional Relationships(s)
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1 We provide evidence that ARHGEF7 might act as a guanine nucleotide exchange factor for LRRK2 and that R1441C mutant LRRK2 with reduced GTP hydrolysis activity also shows reduced binding to ARHGEF7. Guanosine Triphosphate leucine rich repeat kinase 2 Homo sapiens