Title : Different kinetic properties of the two mutants, RAS2Ile152 and RAS2Val19, that suppress the CDC25 requirement in RAS/adenylate cyclase pathway in Saccharomyces cerevisiae.

Pub. Date : 1990 Jan 25

PMID : 2104846






1 Functional Relationships(s)
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1 Our kinetic results show that the functional modifications of RAS2 compensating for the CDC25 inactivation can not only be associated with the presence of a long-lived RAS2.GTP complex, but also with a rapid GDP to GTP exchange reaction. Guanosine Diphosphate Ras family guanine nucleotide exchange factor CDC25 Saccharomyces cerevisiae S288C