Protein Name Ras family guanine nucleotide exchange factor CDC25
Organism Saccharomyces cerevisiae S288C
Gene ID 851019
Gene Symbol

CDC25

UniProt P04821 (CDC25_YEAST)
Relationships Total Number of functionally related compound(s) : 50
Total Number of Articles : 106
Description

Ras family guanine nucleotide exchange factor CDC25

Gene Summary

Enables guanyl-nucleotide exchange factor activity. Involved in Ras protein signal transduction and traversing start control point of mitotic cell cycle. Located in several cellular components, including cytosol; endoplasmic reticulum membrane; and nucleus. Human ortholog(s) of this gene implicated in Noonan syndrome; Noonan syndrome 4; Noonan syndrome 9; and gingival fibromatosis. Orthologous to several human genes including SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1) and SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • Ras family guanine nucleotide exchange factor CDC25
  • YLR310C
  • CTN1
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Properties