Title : Role and mechanism of uncoupling protein 2 on the fatty acid-induced dysfunction of pancreatic alpha cells in vitro.

Pub. Date : 2010 Sep

PMID : 21034559






2 Functional Relationships(s)
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Protein Name
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1 Inhibition of UCP2 influenced the effects of free fatty acid on alpha cells and may relate to glucagon secretion. Fatty Acids, Nonesterified uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus
2 CONCLUSION: UCP2 played an important role on alpha cell dysfunction induced by free fatty acid in vitro, which may be related to its effects on oxidative stress and insulin signal transduction pathway. Fatty Acids, Nonesterified uncoupling protein 2 (mitochondrial, proton carrier) Mus musculus