Title : α1-Adrenoceptor-mediated contraction of rat aorta is partly mediated via transactivation of the epidermal growth factor receptor.

Pub. Date : 2010 Nov

PMID : 20977469






2 Functional Relationships(s)
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1 Phosphorylation of EGFR and ERK1/2 was measured after short-term phenylephrine or EGF stimulation in aorta segments in the presence of AG1478 and the PI3K inhibitor, wortmannin. Phenylephrine epidermal growth factor receptor Rattus norvegicus
2 Phenylephrine induced phosphorylation of EGFR, which was partially blocked by AG1478. Phenylephrine epidermal growth factor receptor Rattus norvegicus