Title : Marek's disease virus type 1 microRNA miR-M3 suppresses cisplatin-induced apoptosis by targeting Smad2 of the transforming growth factor beta signal pathway.

Pub. Date : 2011 Jan

PMID : 20962090






3 Functional Relationships(s)
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1 Marek"s disease virus type 1 microRNA miR-M3 suppresses cisplatin-induced apoptosis by targeting Smad2 of the transforming growth factor beta signal pathway. Cisplatin membrane associated ring-CH-type finger 8 Homo sapiens
2 The results showed that of the total 14 miRNAs encoded by MDV1, MDV1-miR-M3 significantly promoted cell survival under treatment with cisplatin, a widely used chemotherapy drug. Cisplatin membrane associated ring-CH-type finger 8 Homo sapiens
3 MDV1-miR-M3 suppressed cisplatin-induced apoptosis by directly downregulating expression at the protein but not the mRNA level of Smad2, a critical component in the transforming growth factor beta signal pathway. Cisplatin membrane associated ring-CH-type finger 8 Homo sapiens