Title : Molecular basis of the mixed lineage leukemia-menin interaction: implications for targeting mixed lineage leukemias.

Pub. Date : 2010 Dec 24

PMID : 20961854






1 Functional Relationships(s)
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1 Using (13)C-detected NMR experiments, we have mapped the residues within the intrinsically unstructured fragment of MLL that are required for binding to menin. Carbon lysine methyltransferase 2A Homo sapiens