Title : TGF-β1-Induced Expression of the Anti-Apoptotic PAI-1 Protein Requires EGFR Signaling.

Pub. Date : 2009

PMID : 20953304






1 Functional Relationships(s)
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1 PAI-1 induction and ERK pathway activation in response to TGF-beta1 was attenuated by EGFR signaling blockade (with AG1478) or preincubation with the MMP/ADAM inhibitor GM6001. N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide mitogen-activated protein kinase 1 Homo sapiens