Title : Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1.

Pub. Date : 2011 Jan 2

PMID : 20951653






2 Functional Relationships(s)
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1 7,8-Dihydro-8-oxogaunine (8-oxodG) is one of the most abundant oxidative guanine lesions, and 8-oxoguanine DNA glycosylase (OGG1) is involved in its removal. Guanine 8-oxoguanine DNA glycosylase Homo sapiens
2 In this study, we examined if telomeric DNA is particularly susceptible to oxidative base damage and if telomere-specific factors affect the incision of oxidized guanines by OGG1. Guanine 8-oxoguanine DNA glycosylase Homo sapiens