Pub. Date : 2011 Feb
PMID : 20943719
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ZD6474 (vandetanib) is an ATP-competitive inhibitor of RET, epidermal growth factor receptor (EGFR), and vascular endothelial growth factor receptors kinases. | vandetanib | epidermal growth factor receptor | Homo sapiens |
| 2 | ZD6474 (vandetanib) is an ATP-competitive inhibitor of RET, epidermal growth factor receptor (EGFR), and vascular endothelial growth factor receptors kinases. | vandetanib | epidermal growth factor receptor | Homo sapiens |
| 3 | ZD6474 (vandetanib) is an ATP-competitive inhibitor of RET, epidermal growth factor receptor (EGFR), and vascular endothelial growth factor receptors kinases. | vandetanib | epidermal growth factor receptor | Homo sapiens |
| 4 | ZD6474 (vandetanib) is an ATP-competitive inhibitor of RET, epidermal growth factor receptor (EGFR), and vascular endothelial growth factor receptors kinases. | vandetanib | epidermal growth factor receptor | Homo sapiens |
| 5 | This suggests that simultaneous inhibition of RET and EGFR by ZD6474 may overcome the risk of MTC cells to escape from RET blockade through compensatory over-activation of EGFR. | vandetanib | epidermal growth factor receptor | Homo sapiens |
| 6 | This suggests that simultaneous inhibition of RET and EGFR by ZD6474 may overcome the risk of MTC cells to escape from RET blockade through compensatory over-activation of EGFR. | vandetanib | epidermal growth factor receptor | Homo sapiens |