Title : Manganese induces tau hyperphosphorylation through the activation of ERK MAPK pathway in PC12 cells.

Pub. Date : 2011 Jan

PMID : 20937724






2 Functional Relationships(s)
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1 The mitogen-activated protein kinase kinase-1 (MEK1) inhibitor PD98059, which inhibits the activation of ERK MAPK, partially attenuated manganese-induced tau hyperphosphorylation and cytotoxicity. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen activated protein kinase kinase 1 Rattus norvegicus
2 The mitogen-activated protein kinase kinase-1 (MEK1) inhibitor PD98059, which inhibits the activation of ERK MAPK, partially attenuated manganese-induced tau hyperphosphorylation and cytotoxicity. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen activated protein kinase kinase 1 Rattus norvegicus