Pub. Date : 2011 Jan
PMID : 20932827
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we show that nicotine exposure attenuates EAE severity and that this effect is largely abolished in nAChR alpha7 subunit knock-out mice. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 2 | Diverse effects of nicotine on effector and regulatory T cells, as well as antigen-presenting cells, may be linked to differential expression patterns of nAChR subunits across these cell types. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |
| 3 | Taken together, our data show that although alpha7-nAChRs indeed seem to play an important role in nicotine-conferred reduction of the CNS inflammatory response and protection against EAE, other nAChR subtypes also are involved in the anti-inflammatory properties of the cholinergic system. | Nicotine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |