Title : Protective, antioxidative and antiapoptotic effects of 2-methoxy-6-acetyl-7-methyljuglone from Polygonum cuspidatum in PC12 cells.

Pub. Date : 2011 Mar

PMID : 20922651






1 Functional Relationships(s)
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1 T-BHP induced the phosphorylation of ERK 1/2, JNK and p38 MAPK, which were all impeded by pretreatments with MAM, indicating that MAM may act as a potent antioxidant which significantly interferes with the MAPK apoptotic cascades, probably rescuing cells by inhibiting the death pathways. tert-Butylhydroperoxide mitogen-activated protein kinase 8 Rattus norvegicus