Title : CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes.

Pub. Date : 2010 Dec 10

PMID : 20889506






1 Functional Relationships(s)
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1 Paradoxically, we found that inhibition of PLCgamma1 phosphorylation by the general PLC inhibitor U73122 was associated with a delayed and reduced phosphorylation of ERK1/2 and reduced migration of T lymphocytes on fibronectin. 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione phospholipase C gamma 1 Homo sapiens