Title : Placental malnutrition changes the regulatory network of renal Na-ATPase in adult rat progeny: Reprogramming by maternal α-tocopherol during lactation.

Pub. Date : 2011 Jan 1

PMID : 20887709






1 Functional Relationships(s)
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1 Here we investigated the molecular mechanisms by which increased formation of reactive oxygen species during prenatal malnutrition affects the pathways that couple angiotensin II (Ang II) receptors (AT(1)R and AT(2)R) to kidney Na(+)-ATPase in adulthood, and how maternal treatment with alpha-tocopherol can prevent alterations in the main regulatory cascade of the pump. Reactive Oxygen Species angiotensin II receptor, type 1a Rattus norvegicus