Title : Signaling and cytotoxic functions of 4-hydroxyalkenals.

Pub. Date : 2010 Dec

PMID : 20858748






1 Functional Relationships(s)
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1 The aldehyde product 4-hydroxy-2E-nonenal (4-HNE) is the peroxidation product of n-6 PUFAs, such as arachidonic and linoleic acids and their 15-lipoxygenase metabolites, namely 15-hydroperoxyeicosatetraenoic acid (15-HpETE) and 13-hydroperoxyoctadecadienoic acid (13-HpODE). arachidonic arachidonate 15-lipoxygenase Homo sapiens