Title : Oleic acid inhibits stearic acid-induced inhibition of cell growth and pro-inflammatory responses in human aortic endothelial cells.

Pub. Date : 2010 Dec

PMID : 20852092






3 Functional Relationships(s)
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1 Stearic acid-induced phosphorylation of nuclear factor-kappa B (NF-kappaB), a transcriptional regulator of ICAM-1, was also reduced by oleic acid. Oleic Acid nuclear factor kappa B subunit 1 Homo sapiens
2 Stearic acid-induced phosphorylation of nuclear factor-kappa B (NF-kappaB), a transcriptional regulator of ICAM-1, was also reduced by oleic acid. Oleic Acid nuclear factor kappa B subunit 1 Homo sapiens
3 Our data suggest that oleic acid has the ability to reduce the inflammatory effects of long-chain SFAs in HAECs through reducing cellular stearic acid incorporation and NF-kappaB activation. Oleic Acid nuclear factor kappa B subunit 1 Homo sapiens