Title : Epidermal growth factor receptor transactivation by endogenous vasoactive peptides contributes to hyperproliferation of vascular smooth muscle cells of SHR.

Pub. Date : 2010 Dec

PMID : 20852045






1 Functional Relationships(s)
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1 These data suggest that endogenous vasoactive peptides, through increased oxidative stress and resultant activation of c-Src, transactivate EGF-R, which through mitogen-activated protein (MAP) kinase signaling may contribute to the hyperproliferation of VSMC from SHR. vsmc epidermal growth factor receptor Rattus norvegicus