Title : Metformin treatment may increase omentin-1 levels in women with polycystic ovary syndrome.

Pub. Date : 2010 Dec

PMID : 20852028






1 Functional Relationships(s)
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1 In vitro migration and angiogenesis were significantly increased in serum from PCOS women (P < 0.01) compared with matched control subjects; these effects were significantly attenuated by metformin treatment (P < 0.01) plausibly through the regulation of omentin-1 levels via NF-kappaB and Akt pathways. Metformin nuclear factor kappa B subunit 1 Homo sapiens