Pub. Date : 2010 Jan 1
PMID : 20844597
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role for PKC delta in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells. | Fenretinide | protein kinase C delta | Homo sapiens |
| 2 | In the current paper, the role of PKC delta was examined in fenretinide-induced apoptosis in lymphoid leukemia cells. | Fenretinide | protein kinase C delta | Homo sapiens |
| 3 | The antioxidant Vitamin C prevented fenretinide-induced PKC delta cleavage and protected cells from fenretinide. | Fenretinide | protein kinase C delta | Homo sapiens |
| 4 | Suppression of PKC delta expression by shRNA sensitized cells to fenretinide-induced apoptosis possibly by a mechanism involving ROS production. | Fenretinide | protein kinase C delta | Homo sapiens |
| 5 | Now we have found that fenretinide-induced MCL-1 degradation may involve PKC delta as cleavage of the kinase correlated with loss of MCL-1 even in cells when JNK was not activated. | Fenretinide | protein kinase C delta | Homo sapiens |
| 6 | These results suggest that PKC delta may play a complex role in fenretinide-induced apoptosis and may be targeted in antileukemia strategies that utilize fenretinide. | Fenretinide | protein kinase C delta | Homo sapiens |
| 7 | These results suggest that PKC delta may play a complex role in fenretinide-induced apoptosis and may be targeted in antileukemia strategies that utilize fenretinide. | Fenretinide | protein kinase C delta | Homo sapiens |