PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20844597-0 2010 Role for PKC delta in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells. Fenretinide 22-33 protein kinase C delta Homo sapiens 9-18 20844597-2 2010 In the current paper, the role of PKC delta was examined in fenretinide-induced apoptosis in lymphoid leukemia cells. Fenretinide 60-71 protein kinase C delta Homo sapiens 34-43 20844597-5 2010 The antioxidant Vitamin C prevented fenretinide-induced PKC delta cleavage and protected cells from fenretinide. Fenretinide 36-47 protein kinase C delta Homo sapiens 56-65 20844597-6 2010 Suppression of PKC delta expression by shRNA sensitized cells to fenretinide-induced apoptosis possibly by a mechanism involving ROS production. Fenretinide 65-76 protein kinase C delta Homo sapiens 15-24 20844597-8 2010 Now we have found that fenretinide-induced MCL-1 degradation may involve PKC delta as cleavage of the kinase correlated with loss of MCL-1 even in cells when JNK was not activated. Fenretinide 23-34 protein kinase C delta Homo sapiens 73-82 20844597-9 2010 These results suggest that PKC delta may play a complex role in fenretinide-induced apoptosis and may be targeted in antileukemia strategies that utilize fenretinide. Fenretinide 64-75 protein kinase C delta Homo sapiens 27-36 20844597-9 2010 These results suggest that PKC delta may play a complex role in fenretinide-induced apoptosis and may be targeted in antileukemia strategies that utilize fenretinide. Fenretinide 154-165 protein kinase C delta Homo sapiens 27-36