Pub. Date : 2011 Jan 20
PMID : 20838377
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis. | Guanine Nucleotides | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 2 | Guanine nucleotides regulate sphingosine kinase 1 activation by eukaryotic elongation factor 1A and provide a mechanism for eEF1A-associated oncogenesis. | Guanine Nucleotides | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 3 | Here, we show that the guanine nucleotide-bound state of eEF1A regulates its ability to activate SK1, with eEF1A.GDP, but not eEF1A.GTP, enhancing SK1 activity in vitro. | Guanine Nucleotides | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 4 | Here, we show that the guanine nucleotide-bound state of eEF1A regulates its ability to activate SK1, with eEF1A.GDP, but not eEF1A.GTP, enhancing SK1 activity in vitro. | Guanine Nucleotides | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 5 | Here, we show that the guanine nucleotide-bound state of eEF1A regulates its ability to activate SK1, with eEF1A.GDP, but not eEF1A.GTP, enhancing SK1 activity in vitro. | Guanine Nucleotides | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 6 | Furthermore, we show that enhancing cellular eEF1A.GDP levels through expression of a guanine nucleotide dissociation inhibitor of eEF1A, translationally controlled tumour protein (TCTP), increased SK1 activity in cells. | Guanine Nucleotides | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |
| 7 | Furthermore, we show that enhancing cellular eEF1A.GDP levels through expression of a guanine nucleotide dissociation inhibitor of eEF1A, translationally controlled tumour protein (TCTP), increased SK1 activity in cells. | Guanine Nucleotides | eukaryotic translation elongation factor 1 alpha 1 | Homo sapiens |