Title : Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

Pub. Date : 2010 Dec

PMID : 20837989






1 Functional Relationships(s)
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1 These findings suggest that ns-SNPs in human AKR1C3, AKR1C4, and AKR7A2 significantly decrease the in vitro metabolism of DOX and DAUN. Doxorubicin aldo-keto reductase family 7 member A2 Homo sapiens