Title : Sirolimus-induced isometric tubular vacuolization: a new sirolimus histopathologic manifestation.

Pub. Date : 2010 Sep

PMID : 20832541






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1 In this case report, we introduce a new morphological appearance after sirolimus therapy of isometric cytoplasmic vacuolization of the renal tubules and severe arterial hyalinosis, similar to that seen in calcineurin inhibitor induced tubular toxicity. Sirolimus calcineurin binding protein 1 Homo sapiens