Title : Anti-stress effects of ginseng via down-regulation of tyrosine hydroxylase (TH) and dopamine β-hydroxylase (DBH) gene expression in immobilization-stressed rats and PC12 cells.

Pub. Date : 2010 Aug

PMID : 20827341






2 Functional Relationships(s)
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Protein Name
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1 Nicotine as a ligand of the nicotinic acetylcholine receptor (nAChR) in adrenal medulla stimulates catecholamine secretion and activates TH and DBH gene expression. Nicotine tyrosine hydroxylase Rattus norvegicus
2 Nicotine treatment increased mRNA levels of TH and DBH by 3.3- and 3.1-fold in PC12 cells. Nicotine tyrosine hydroxylase Rattus norvegicus