Pub. Date : 2010 Oct
PMID : 20811386
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure. | Simendan | angiotensinogen | Rattus norvegicus |
| 2 | However, levosimendan improved systolic function, decreased cardiac atrial natriuretic peptide mRNA expression, ameliorated Ang II-induced cardiac damage and decreased mortality. | Simendan | angiotensinogen | Rattus norvegicus |
| 3 | Our findings suggest that levosimendan ameliorates Ang II-induced hypertensive heart failure and reduces mortality. | Simendan | angiotensinogen | Rattus norvegicus |
| 4 | The results also support the notion that the effects of levosimendan in dTGRs are mediated by blood pressure-independent mechanisms and include improved systolic function and amelioration of Ang II-induced coronary and cardiomyocyte damage. | Simendan | angiotensinogen | Rattus norvegicus |