Title : Sex differences in UDP-glucuronosyltransferase 2B17 expression and activity.

Pub. Date : 2010 Dec

PMID : 20810538






1 Functional Relationships(s)
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1 Consistent with the increased expression of UGT2B17 in men, HLM from men also had a higher level of glucuronidation activity than HLM from women against three UGT2B17 substrates: 3-fold higher for 17-dihydroexemestane (p = 0.002); 3-fold higher for 3-hydroxycotinine (p < 0.001); and 1.5-fold higher for suberoylanilide hydroxamic acid (p = 0.014). hydroxycotinine UDP glucuronosyltransferase family 2 member B17 Homo sapiens