Pub. Date : 2010 Oct 6
PMID : 20802462
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Disulphide production by Ero1alpha-PDI relay is rapid and effectively regulated. | disulphide | prolyl 4-hydroxylase subunit beta | Homo sapiens |
| 2 | Both the oxidase Ero1alpha and the oxidoreductase protein disulphide isomerase (PDI) strongly contribute to the rapid recovery kinetics, but experiments in ERO1-deficient cells indicate the existence of parallel pathways for disulphide generation. | disulphide | prolyl 4-hydroxylase subunit beta | Homo sapiens |
| 3 | We find PDI to be the main substrate of Ero1alpha, and mixed-disulphide complexes of Ero1 primarily form with PDI, to a lesser extent with the PDI-family members ERp57 and ERp72, but are not detectable with another homologue TMX3. | disulphide | prolyl 4-hydroxylase subunit beta | Homo sapiens |
| 4 | We find PDI to be the main substrate of Ero1alpha, and mixed-disulphide complexes of Ero1 primarily form with PDI, to a lesser extent with the PDI-family members ERp57 and ERp72, but are not detectable with another homologue TMX3. | disulphide | prolyl 4-hydroxylase subunit beta | Homo sapiens |