Title : The proliferative and morphologic responses of a colon carcinoma cell line (LIM 1215) require the production of two autocrine factors.

Pub. Date : 1991 Aug

PMID : 2072905






1 Functional Relationships(s)
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1 In addition, the EGF receptor was found to be phosphorylated on tyrosine in LIM 1215 cells proliferating at high density, suggesting that the autocrine production of transforming growth factor alpha (TGF alpha) and subsequent ligation to the EGF receptor was occurring. Tyrosine transforming growth factor alpha Homo sapiens