Title : Identification and characterization of novel oncogenes in chronic eosinophilic leukemia and T-cell acute lymphoblastic leukemia.

Pub. Date : 2010

PMID : 20726440






1 Functional Relationships(s)
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1 Sorafenib was originally developed as a BRAF inhibitor, but our work demonstrates that sorafenib can also be used to treat FIP1L1-PDGFRA positive leukemia, demonstrating that new therapies to treat rare leukemias may be simply found by testing drugs that are already in use for the treatment of other diseases. Sorafenib B-Raf proto-oncogene, serine/threonine kinase Homo sapiens