Title : Alpha-synuclein in alpha-helical conformation at air-water interface: implication of conformation and orientation changes during its accumulation/aggregation.

Pub. Date : 2010 Sep 28

PMID : 20714568






1 Functional Relationships(s)
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1 Alpha-synuclein, a natively unstructured protein important in the neuropathology of Parkinson"s disease, was found to form a Langmuir monolayer in an alpha-helical conformation with its helical axis parallel to the air-water interface. Water synuclein alpha Homo sapiens