Title : First-line therapy and methylation status of CHFR in serum influence outcome to chemotherapy versus EGFR tyrosine kinase inhibitors as second-line therapy in stage IV non-small-cell lung cancer patients.

Pub. Date : 2011 Apr

PMID : 20705357






2 Functional Relationships(s)
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1 Patients who had received first-line docetaxel/cisplatin attained an overall survival of 19.2 months when treated with second-line EGFR TKIs, in comparison with 10.7 months when treated with second-line chemotherapy (P = 0.0002). Cisplatin epidermal growth factor receptor Homo sapiens
2 Second-line EGFR TKIs improved survival in patients receiving first-line cisplatin-based treatment. Cisplatin epidermal growth factor receptor Homo sapiens