Title : The NF (Nuclear factor)-κB inhibitor parthenolide interacts with histone deacetylase inhibitors to induce MKK7/JNK1-dependent apoptosis in human acute myeloid leukaemia cells.

Pub. Date : 2010 Oct

PMID : 20701602






2 Functional Relationships(s)
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Protein Name
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1 Co-administration of parthenolide blocked HDACI-mediated phosphorylation/activation of IKK and RelA/p65 in association with increased JNK1 activation in various AML cell types. parthenolide RELA proto-oncogene, NF-kB subunit Homo sapiens
2 Co-administration of parthenolide blocked HDACI-mediated phosphorylation/activation of IKK and RelA/p65 in association with increased JNK1 activation in various AML cell types. parthenolide RELA proto-oncogene, NF-kB subunit Homo sapiens