Title : Modanifil activates the histaminergic system through the orexinergic neurons.

Pub. Date : 2010 Oct 15

PMID : 20696213






2 Functional Relationships(s)
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1 Modafinil is also thought to express its effect through the orexinergic neurons, and orexin increases hypothalamic histamine release. Modafinil hypocretin Mus musculus
2 In the present study, we performed in vivo microdialysis and c-Fos immunohistochemistry to investigate whether the orexinergic system mediates the activation of the histaminergic system by modafinil using orexin neuron-deficient mice. Modafinil hypocretin Mus musculus