Title : [Comparative thermodynamic analysis of thrombin interaction with anti-thrombin aptamers and their heterodimeric construct].

Pub. Date : 2010 May-Jun

PMID : 20695220






1 Functional Relationships(s)
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1 Aptamers interacting selectively with the anion-binding exosites 1 and 2 of thrombin were merged into dimeric oligonucleotide constructs with use of a poly-(dT)-linker of 35 nucleotides (nt) long. Oligonucleotides coagulation factor II, thrombin Homo sapiens