Title : Discovery of pyrrole-indoline-2-ones as Aurora kinase inhibitors with a different inhibition profile.

Pub. Date : 2010 Aug 26

PMID : 20681538






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Compounds 47 and 36 (the ethyl ester analogue of 33) inhibited the proliferation of HCT-116 and HT-29 cells and suppressed levels of the phosphorylated substrates of Aurora A and Aurora B in the Western blots. ethyl ester aurora kinase B Homo sapiens