Pub. Date : 2010 Oct
PMID : 20678573
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that the corticosterone-inactivating enzyme 11beta-hydroxysteroid dehydrogenase type 2 (HSD2) was up-regulated 7 days after lesion in freeze-injured nerve. | Corticosterone | hydroxysteroid 11-beta dehydrogenase 2 | Homo sapiens |
| 2 | We found that the corticosterone-inactivating enzyme 11beta-hydroxysteroid dehydrogenase type 2 (HSD2) was up-regulated 7 days after lesion in freeze-injured nerve. | Corticosterone | hydroxysteroid 11-beta dehydrogenase 2 | Homo sapiens |
| 3 | The maintenance of a low intracellular level of corticosterone by HSD2 activity in the regenerating nerve is concordant with the improvement of nervous function in injured animals (as measured by walking ability) after treatment by the GR antagonist mifepristone and with the reduction in GR participation in accumulation of the mRNA for numerous endogenous genes (from the renin-angiotensin system and other classical mineralocorticoid-responsive genes), in the same animals. | Corticosterone | hydroxysteroid 11-beta dehydrogenase 2 | Homo sapiens |