Title : NF-κB localization in multiple myeloma plasma cells and mesenchymal cells.

Pub. Date : 2011 Jan

PMID : 20674018






2 Functional Relationships(s)
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1 In addition, the proteasome inhibitor Bortezomib, which is described to antagonize NF-kappaB activity, had a consistent antitumor activity against both chemoresistant and chemosensitive MM-cells, regardless the NF-kappaB localization, thus suggesting the existence of other molecular targets of proteasome inhibitors in MM. Bortezomib nuclear factor kappa B subunit 1 Homo sapiens
2 In addition, the proteasome inhibitor Bortezomib, which is described to antagonize NF-kappaB activity, had a consistent antitumor activity against both chemoresistant and chemosensitive MM-cells, regardless the NF-kappaB localization, thus suggesting the existence of other molecular targets of proteasome inhibitors in MM. Bortezomib nuclear factor kappa B subunit 1 Homo sapiens