Title : Cirrhotic rat liver: reference to transporter activity and morphologic changes in bile canaliculi--gadoxetic acid-enhanced MR imaging.

Pub. Date : 2010 Sep

PMID : 20663976






3 Functional Relationships(s)
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1 CONCLUSION: Findings showed that liver cirrhosis promotes the elimination of gadoxetic acid mediated by mrp2; therefore, mrp2 up-regulation may explain the significant signal intensity loss noted on gadoxetic acid-enhanced MR images in the rat. gadolinium ethoxybenzyl DTPA ATP binding cassette subfamily C member 2 Rattus norvegicus
2 CONCLUSION: Findings showed that liver cirrhosis promotes the elimination of gadoxetic acid mediated by mrp2; therefore, mrp2 up-regulation may explain the significant signal intensity loss noted on gadoxetic acid-enhanced MR images in the rat. gadolinium ethoxybenzyl DTPA ATP binding cassette subfamily C member 2 Rattus norvegicus
3 CONCLUSION: Findings showed that liver cirrhosis promotes the elimination of gadoxetic acid mediated by mrp2; therefore, mrp2 up-regulation may explain the significant signal intensity loss noted on gadoxetic acid-enhanced MR images in the rat. gadolinium ethoxybenzyl DTPA ATP binding cassette subfamily C member 2 Rattus norvegicus