Pub. Date : 2010 Aug
PMID : 20647331
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The importance of the p53 pathway to PIM1-driven cellular senescence was further shown by the observation that expression of dominant-negative p53 or shRNA targeting p21 blocked the PIM1-induced changes in the DNA damage response and increases in SA-beta-Gal activity. | 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid | Pim-1 proto-oncogene, serine/threonine kinase | Homo sapiens |
2 | The importance of the p53 pathway to PIM1-driven cellular senescence was further shown by the observation that expression of dominant-negative p53 or shRNA targeting p21 blocked the PIM1-induced changes in the DNA damage response and increases in SA-beta-Gal activity. | 2-(2-quinolinyl)-1H-indene--1,3(2H)-dione-6'-sulfonic acid | Pim-1 proto-oncogene, serine/threonine kinase | Homo sapiens |