Title : Substrate and product analogues as human O-GlcNAc transferase inhibitors.

Pub. Date : 2011 Mar

PMID : 20640461






2 Functional Relationships(s)
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1 Protein glycosylation on serine/threonine residues with N-acetylglucosamine (O-GlcNAc) is a dynamic, inducible and abundant post-translational modification. Acetylglucosamine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens
2 In metazoa, a single, highly conserved and essential gene encodes the O-GlcNAc transferase (OGT) that transfers GlcNAc onto substrate proteins using UDP-GlcNAc as the sugar donor. Acetylglucosamine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens