Title : Anti-inflammatory effects of pioglitazone on iron-induced oxidative injury in the nigrostriatal dopaminergic system.

Pub. Date : 2010 Dec

PMID : 20626630






1 Functional Relationships(s)
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1 However, pioglitazone inhibited iron-induced alpha-synuclein aggregation, elevations in interleukin-1beta and interleukin-6 mRNA levels as well as increases in oxygenase-1, cyclo-oxygenase II, nitric oxide synthase and ED-1 protein levels, an indicator of activated microglia. Iron interleukin 6 Rattus norvegicus