Title : Synergistically enhanced CYP2B6 inducibility between a polymorphic mutation in CYP2B6 promoter and pregnane X receptor activation.

Pub. Date : 2010 Oct

PMID : 20624854






2 Functional Relationships(s)
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1 Cell-based promoter reporter assays demonstrated that CYP2B6 luciferase activity was synergistically enhanced in the presence of both -82T C mutation and rifampicin (RIF)-activated PXR. Rifampin cytochrome P450 family 2 subfamily B member 6 Homo sapiens
2 Cell-based promoter reporter assays demonstrated that CYP2B6 luciferase activity was synergistically enhanced in the presence of both -82T C mutation and rifampicin (RIF)-activated PXR. Rifampin cytochrome P450 family 2 subfamily B member 6 Homo sapiens