Title : At the crossroads of steroid hormone biosynthesis: the role, substrate specificity and evolutionary development of CYP17.

Pub. Date : 2011 Jan

PMID : 20619364






1 Functional Relationships(s)
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1 CYP17 catalyzes the 17alpha-hydroxylation reaction of delta4-C21 steroids (progesterone derivatives) and delta5-C21 steroids (pregnenolone derivatives) as well as the 17,20-lyase reaction producing C19-steroids, a key branch point in steroid hormone biosynthesis. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens