Title : Molecular mechanism of angiotensin II-induced insulin resistance in aortic vascular smooth muscle cells: roles of Protein Tyrosine Phosphatase-1B.

Pub. Date : 2010 Sep-Oct

PMID : 20601126






1 Functional Relationships(s)
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1 We found that Ang II significantly inhibited insulin-induced phosphorylation of tyrosine 608 of IRS-1 and serine 473 of Akt, a downstream member of anti-mitogenic pathway of insulin. Tyrosine angiotensinogen Homo sapiens