Title : Caffeic acid phenethyl ester-mediated Nrf2 activation and IkappaB kinase inhibition are involved in NFkappaB inhibitory effect: structural analysis for NFkappaB inhibition.

Pub. Date : 2010 Sep 15

PMID : 20599928






1 Functional Relationships(s)
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1 In HCT116 cells, CAPE interfered with TNF-alpha dependent IkappaBalpha degradation and subsequent nuclear accumulation of p65, which occurred by direct inhibition of inhibitory protein kappaB kinase (IKK). caffeic acid phenethyl ester NFKB inhibitor alpha Homo sapiens