Title : The frequency-dependence of the nicotine-induced inhibition of dopamine is controlled by the α7 nicotinic receptor.

Pub. Date : 2010 Sep

PMID : 20598018






1 Functional Relationships(s)
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1 Surprisingly, a high dose of nicotine (2 muM; capable of interacting with additional nAChR subtypes) produced an inhibition of dopamine evoked by high frequency stimulation, an effect that was not seen with the low dose of nicotine or the beta2 antagonist, dihydro-beta-erythroidine hydrobromide. Dopamine cholinergic receptor nicotinic alpha 4 subunit Homo sapiens